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Selective Estrogen Receptor Modulators (Contemporary Endocrinology)
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Discount Medical Books > Endocrinology > Item 95
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Selective Estrogen Receptor Modulators (Contemporary Endocrinology)
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by Andrea Manni and Michael Verderame
Sales Rank: 3233162
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List Price: $175.00
$175.00
At Amazon
on 9-5-2008.
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Hardcover: 384 pages
Publisher: Humana Press; 1st edition December 15, 2001
Language: English
ISBN-10: 0896039129
ISBN-13: 978-0896039124
Product Dimensions:
10.2 x 7.3 x 1 inches
Shipping Weight: 2.4 pounds
Product Review
"this book is densely packed with data will be valuable for investigators in the field as well as those new to this area. There are many details of interest to the molecular endocrinologist. The clinical information is also intriguing for the clinician who needs to know how to apply the SERMs in the management of postmenopausal problems." - Oncology
"Selective Estrogen Receptor Modulators: Research and Clinical Application is an indispensable resource for evaluating the use of SERM potential alternatives to estrogens. The book synthesizes the current understanding of SERM at the levels of molecular mechanisms and clinical applications and provides a precise and balanced view of ongoing research and future developments. Clearly written and supported by informative illustrations, it is aimed at a specialized audience and should be particularly useful to researchers and clinicians eager to advance their knowledge of these so-called 'designer estrogens'. Selective Estrogen Receptor Modulators is an excellent collection of timely reviews. Its major strength is combining basic and clinical studies in a thorough account of current knowledge about estrogens and SERM." -Trends in Endocrinology and Metabolism
Product Description
Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the development of the ideal SERM-on the complex mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity and contribute to its crosstalk with growth factor signaling. The clinical presentation reviews the data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment and prevention, as well as their effects on the reproductive, vascular, skeletal, and central nervous systems. A tentative approach to menopause-related health issues is also provided for women with and without a previous diagnosis of localized breast cancer.
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Selective Estrogen Receptor Modulators (Contemporary Endocrinology)
Available from Amazon
Price: $175.00
Updated on 9-5-2008.
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