Vascular Disease: Molecular Biology and Gene Transfer Protocols (Methods in Molecular Medicine)... by Andrew H. Baker Sales Rank: 3925138 List Price: $130.00 $130.00 At Amazon on 10-16-2008.

Hardcover: 456 pages Publisher: Humana Press; 1 edition August 1, 1999 Language: English ISBN-10: 0896037312 ISBN-13: 978-0896037311 Product Dimensions: 9.1 x 6.1 x 1.3 inches Shipping Weight: 1.9 pounds Product Review "The chapters are clearly written so that complex techniques are reduced to their individual componentsthis book will be a major asset to a molecular biology laboratory involved in vascular research."-Atherosclerosis "This collection of very detailed molecular biology protocols was compiledThe first five parts present protocols that are designed to identity and characterize genes in cardiovascular disease, including methods for detecting specific gene mutation, identifying new genes, characterizing the levels and regulation of expression of the new genes, and apoptotic methods. The final two parts contain in vivo and in culture gene transfer protocols used in cardiovascular disease and protocols for clinical gene therapy.an excellent reference for molecular biologists in the field of vascular disease." - Quarterly Review of Biology "the authors of the individual chapters have made every effort to relate their particular techniques to the study of vascular tissues.the editor has assembled a broad base of well established authors to describe their protocols.this is a good book.this book may prove worthwhile in helping to ease the load on the typical physician-scientist trying to care for patients and at the same time direct his or her laboratory research program."- Texas Heart Institute Journal "The book is the result of the contribution of distinguished experts in the field. Each chapter of the book is introduced by a theoretical summary of the goal of the technique with excellent diagrams followed by the material used, the basic procedures and the methods. Critical notes and references end each chapter. This important publication directed to molecular biologists covers the latest aspects of molecular procedures for the study of cardiovascular diseases and confirms, if necessary, the irreversible revolution in cardiovascular research."- Acta Cardiologica Product Description Andrew Baker and a noted panel of expert investigators describe today's most powerful molecular methods for investigating the pathogenesis of vascular disease. These detailed, easy-to-follow techniques range from methods that have been used successfully to identify specific mutations involved in cardiovascular disorders, to those for transferring genes associated with cardiovascular disease into various vascular cell types by in vitro and in vivo routes. There are methods to identify novel genes and generate full-length cDNAs, to study gene transcription and promoter activity easily and effectively, and to ascertain precisely gene expression levels within the individual cell types in different pathophysiological conditions. Vascular Disease: Molecular Biology and Gene Therapy Protocols offers today's vascular biologist and gene therapist an unprecedented ability to study the pathogenesis of vascular disease and readily to probe the potential for gene-based therapies. Vascular Disease: Molecular Biology and Gene Transfer Protocols (Methods in Molecular Medicine)... Available from Amazon Price: $130.00 Updated on 10-16-2008.

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